Drug overdose is a serious public health issue characterized by the consumption of a drug or substance in quantities that are harmful or potentially life-threatening to an individual. This can be intentional, such as in cases of suicide attempts, or unintentional, often due to misuse, abuse, or accidental ingestion of medication. Overdoses can result in a wide range of symptoms and complications, including respiratory depression, coma, organ failure, and death. Research in this area focuses on understanding the causes and risk factors for drug overdose, as well as developing interventions and strategies to prevent overdoses, improve treatment outcomes, and reduce harm associated with substance use. Studies also examine the impact of overdose on individuals, communities, and healthcare systems, as well as the effectiveness of harm reduction programs and policies aimed at addressing this issue.